By Brent MacDonald
By Brent MacDonald – Principal at Rising Tide VC Precision Nanosystems Inc’s (PNI) mission is to accelerate the creation of transformative medicine that significantly impacts human well being. The Company creates end-to-end solutions that empower researchers to harness powerful nanotechnology to transform our understanding and treatment of rare diseases, cancer, and infectious diseases. Leading academic institutions, […]
By Brent MacDonald
By Brent MacDonald – Principal @ Rising Tide VC Despite cheap, abundant genetics tools and information, many aspects of healthcare research remain constrained and complex. For example, while the cost of DNA sequencing has declined dramatically, innovations in personalized medicine, drug research, and early-stage pharmaceutical discovery and development have not kept up due to constraints […]
By Brent MacDonald
By Brent MacDonald – Principal @ Rising Tide VC George Church, Ph.D., renowned professor of genetics, Harvard Medical School, recently declared for decades, bacteria have been used as the workhorses of the biotech industry in the production of blockbuster therapeutics, and we can dramatically expand their utility by recoding their genomes.[1] Protein therapeutics are often […]
By rent MacDonald
By Brent MacDonald – Principal @ Rising Tide VC Ayar Labs was founded in 2015 and based on 10-years of research and collaboration between MIT, UC Berkeley, and the University of Colorado Boulder, and funding from DARPA. The Company’s patented approach uses industry standard silicon processing techniques to develop high speed, high density, low power […]
By Brent MacDonald
By Brent MacDonald – Principal @ Rising Tide VC Millions of people worldwide are visually impaired due to cataracts – loss of vision due to lens clouding. The two current treatment options, the standard intraocular lens (IOL) and multi-focal IOL, force patients to choose between focusing ability and clear vision. Current treatment options have limitations […]
By Brent MacDonald – Principal @ Rising Tide VC Molecular Assemblies began more than 30 years ago when Bill Efcavitch and Curt Becker, then early founders at the pioneering biotech company Applied Biosystems, commercialized the first practical method of synthesizing DNA. Known as phosphoramidite synthesis[1], this chemical-based method was a significant breakthrough and remains the […]